HYALINE MEMBRANE DISEASE(HMD)
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작성일 23-07-27 04:37
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1. Absence of surfactant
-> high surface tension -> tendency to become atelectatic2. major constituents of surfactant
; dipalmitylphosphatidylcholine(lecithin), phosphatidyl glycerol, apoproteins(SP-A,B,C)3. factors supressing surfactant synthesis
; asphyxia, hypoxemia, pulmonary ischemia, hypovolemia, hypotension, cold stressIII. PATHOLOGY
생후 6-8hr 이전에는 특징적인 소견 나타나지 않음
1. grossly - deep purplish red and liver like in consistency
2. microscopically - alveolar duct, alveoli and bronchiole
-> lined with acidophylic, homogenous, or granular membrane
IV. CLINICAL MANIFESTATION
- tachypnea, prominent grunting, intercostal and subcostal retraction, nasal flaring, duskiness, cyanosis(unresponsive to oxygen therapy)
-> progressive worsening cyanosis & dyspnea, apnea, irregular respiration, mixed respiratory and metabolic acidosis, edema, ileus, oliguria
-…(To be continued )
1. Absence of surfactant -> high surface tension -> tendency to become ate... , HYALINE MEMBRANE DISEASE(HMD)기타레포트 ,
설명
레포트/기타
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-> high surface tension -> tendency to become ate...
,기타,레포트
HYALINE MEMBRANE DISEASE(HMD)
순서
1. Absence of surfactant
다.
